PDE5 Inhibitors As Potential Tools In The Treatment Of Cystic Fibrosis
Despite great advances in the understanding of the genetics and pathophysiology of cystic fibrosis (CF), there is still no cure for the disease.Using phosphodiesterase type 5 (PDE5) inhibitors, we and others have provided evidence of rescued F508del-CFTR trafficking and corrected deficient chloride transport activity.Studies Bag Strap using PDE5 in